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Does Paracetamol in Pregnancy cause autism?

  • Writer: Ed Mullins
    Ed Mullins
  • Sep 22
  • 1 min read

The Trump administration is reported to be about to announce that taking Paracetamol (Acetomenaphin) in Pregnancy causes Autism.

Paracetamol is commonly taken in pregnancy  for pain relief and to treat fever.
Paracetamol is commonly taken in pregnancy for pain relief and to treat fever.

The best available evidence is that paracetamol use in pregnancy does not cause autism. In the absence of any new evidence, this new announcement (yet to be made) would appear to be an unsubstantiated theory which is likely to lead to an essential treatment for fever and pain being denied to women in pregnancy without good reason, contrary to US and European medical guidance.

 

A high-quality review of the evidence in this area, published in the Journal of the American Medical Association Acetaminophen Use During Pregnancy and Children’s Risk of Autism, ADHD, and Intellectual Disability | Attention Deficit/Hyperactivity Disorders | JAMA | JAMA Network, looked not only at whether mothers of children with autism took paracetamol (acetaminophen) during pregnancy but crucially also assessed the existence of known risk factors for autism, why paracetamol was taken ( such as a fever or inflammatory arthritis), whether the parents already had diagnoses like autism and whether the child's siblings had diagnoses like autism (because there is an inheritable element).


It concluded, 'Acetaminophen use during pregnancy was not associated with children’s risk of autism, ADHD, or intellectual disability in sibling control analysis. This suggests that associations observed in other models may have been attributable to familial confounding.'


So if you are pregnant and need treatment for pain or for fever (alongside addressing the cause of the fever), you can take Paracetamol in the knowledge that the best available evidence shows

no link to autism.

 
 
 

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